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ALK — IL2
Text-mined interactions from Literome
Zhang et al., Proc Natl Acad Sci U S A 2011
:
These results demonstrate that the oncogenic tyrosine kinase
NPM-ALK induces epigenetic silencing of the IL-2R? gene and that
IL-2R? acts as a tumor suppressor by reciprocally inhibiting expression of NPM-ALK
Takahashi et al., Hokkaido Igaku Zasshi 1986
:
Although PHA induced ALK activity from thymocytes of LF but not from thymocytes of HF, crude
IL2 induced
ALK activity from both fractions ... The
ALK activity
induced by PHA or
IL2 was abrogated by treatment of OKT3 and complement but not by OKT4 or OKT8 and complement ...
ALK activity and allospecific cytotoxic killer cell ( allo-CTL ) activity were
induced from thymocytes of LF by MLC and from both fractions by MLC with
IL2 , but there were some differences between these two activities