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SOAT1 — TGFB1

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: SOAT1 → TGFB1 (increases) Hori et al., Biochem Biophys Res Commun 2004*
  Evidence: To further elucidate the mechanism for ACAT-1 regulation in macrophages, we examined the effects of five cytokines including transforming growth factor-beta1 (TGF- beta1) on ACAT-1 expression in cultured human monocyte-macrophages. Immunoblot analyses showed that TGF-beta1 increased ACAT-1 protein expression by two- to threefold when added during differentiation of human monocytes into macrophages.

Text-mined interactions from Literome

Hori et al., Biochem Biophys Res Commun 2004 : Immunoblot analyses showed that TGF-beta1 increased ACAT-1 protein expression by two- to threefold when added during differentiation of human monocytes into macrophages ... Since TGF-beta1 is expressed in human atherosclerotic lesions, the current results suggest that ACAT-1 expression in monocytes infiltrating from the circulation to vascular walls may be enhanced by pre existing TGF-beta1
Yamanaka et al., Curr Eye Res 2006 : We also examined the effects of IL-7, PKC inhibitor, and STAT inhibitor on the expressions of TGF-beta1 and type I collagen alpha1 chain ( col1A1 ) m-RNA by using real-time RT-PCR
Park et al., Mol Immunol 2007 (MAP Kinase Signaling System) : We have shown previously that TGF-beta1 inhibits Th1 development by inhibiting IFN-gamma 's induction of T-bet and other Th1 differentiation genes, and that TGF-beta1 inhibits receptor-proximal IFN-gamma-Jak-Stat signaling responses
Zhang et al., Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2007 : To evaluate the effect of JAK/STAT signaling pathway activation on the transdifferentiation and secretion of transforming growth factor-beta1 ( TGF-beta1 ) induced by high glucose in renal proximal tubular epithelial cells