Gene interactions and pathways from curated databases and text-mining

◀ Back to IL6

IL6 — SERPINF1

Text-mined interactions from Literome

Yamagishi et al., J Mol Cell Cardiol 2004 : Pigment epithelium derived factor inhibits TNF-alpha induced interleukin-6 expression in endothelial cells by suppressing NADPH oxidase mediated reactive oxygen species generation ... Accordingly, we investigated effects of PEDF on reactive oxygen species ( ROS ) generation, NF-kappaB activation and interleukin (IL)-6 expression in TNF-alpha exposed HUVEC ... PEDF inhibited TNF-alpha induced expression of IL-6 at both mRNA and protein levels ... The results demonstrated that PEDF inhibited TNF-alpha induced NF-kappaB activation and subsequent IL-6 overexpression in HUVEC by suppressing NADPH oxidase mediated ROS generation
Yoshida et al., Life Sci 2006 : Pigment epithelium derived factor (PEDF) blocks the interleukin-6 signaling to C-reactive protein expression in Hep3B cells by suppressing Rac-1 activation
Smith et al., J Urol 2008 (Prostatic Neoplasms) : The known transdifferentiating agent interleukin-6 induced PEDF secretion