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E2F1 — ESR1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: ESR1 — E2F1 (physical association, affinity chromatography technology) Liu et al., PloS one 2011*

Text-mined interactions from Literome

Wang et al., Mol Endocrinol 1999 (Breast Neoplasms) : Transcriptional activation of E2F1 gene expression by 17beta-estradiol in MCF-7 cells is regulated by NF-Y-Sp1/estrogen receptor interactions
Louie et al., Mol Cancer Res 2010 (Breast Neoplasms) : Estrogen receptor regulates E2F1 expression to mediate tamoxifen resistance ... Faslodex or ICI 182, 780 ( ICI ) -mediated degradation of estrogen receptor ( ER ) reduced the proliferation of these cells, as well as the level of E2F1 expression in tamoxifen-resistant cells, suggesting that tamoxifen resistance and E2F1 expression are in part dependent on ER