Wang et al., Am J Respir Crit Care Med 2002
(Inflammation) :
Moreover, phosphorylation of p38 mitogen activated protein kinase induced by ICAM-1 cross linking occurred only in PMECs and not in PAECs
Wong et al., Am J Respir Cell Mol Biol 2003
:
Therefore, the expression of ICAM-1 might involve both p38 MAPK and NF-kappaB activities, whereas the regulation of CD11b, CD18, and ICAM-3 expressions might be mediated through p38 MAPK but not NF-kappaB
Zhang et al., Br J Pharmacol 2009
:
These findings suggest that Ucn1 exerts pro-inflammatory effects by augmenting LPS induced expression of COX-2 and ICAM-1 in RAECs via CRF ( 2 ) receptors and the activation of p38MAPK and NF-kappaB