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SUCNR1 — VEGFA

Text-mined interactions from Literome

Gnana-Prakasam et al., Invest Ophthalmol Vis Sci 2011 (Hemochromatosis...) : GPR91 , a succinate receptor, is expressed in retinal ganglion cells and induces vascular endothelial growth factor ( VEGF ) expression ... The involvement of GPR91 in succinate induced expression of VEGF in RPE cells was confirmed with GPR91-specific shRNA
Hu et al., Exp Eye Res 2013 (Diabetic Retinopathy...) : Recent research using a rat oxygen induced retinopathy model has demonstrated that the G protein coupled receptor 91 (GPR91) of retinal ganglion neurons is the principal respondent to succinate and consequently induces the release of angiogenic factor vascular endothelial growth factor ( VEGF )