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AKT3 — TWIST1

Text-mined interactions from Literome

Hong et al., J Exp Clin Cancer Res 2009 (Carcinoma, Squamous Cell...) : All of these findings suggest that Akt inhibition could induce the MErT through decreased NF-kappaB signaling and downregulation of Snail and Twist in OSCC cells
Xue et al., Cancer Discov 2012 (Breast Neoplasms...) : Akt/PKB mediated phosphorylation of Twist1 promotes tumor metastasis via mediating cross-talk between PI3K/Akt and TGF-ß signaling axes ... Akt/protein kinase B (PKB) mediated Twist1 phosphorylation promotes EMT and breast cancer metastasis by modulating its transcriptional target TGF-ß2, leading to enhanced TGF-ß receptor signaling, which in turn maintains hyperactive phosphoinositide 3-kinase (PI3K)/Akt signaling
Pai et al., J Mol Med (Berl) 2013 (Breast Neoplasms...) : However, Akt overexpression reversed the inhibitory effects of moscatilin on phospho-Akt protein expression but not its effects on Twist