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FYN — PRKCD

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: PRKCD → FYN (increases, FYN Activity)
  Evidence: in human keratinocytes, E-cadherin/PI3K also activates the terminal differentiation-inducing phospholipase- C-g1 (Xie and Bikle, 2007), whereas the Src tyrosine kinase Fyn can activate protein kinase-Cd, which was suggested to be the major protein kinase-C isoform involved in terminal differentiation downstream of EGF-R (Denning et al., 1995).

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Intact Interaction: PRKCD — FYN (physical association, enzyme linked immunosorbent assay) Ron et al., J Biol Chem 1999*
• IRef Intact Interaction: PRKCD — FYN (phosphorylation reaction, protein kinase assay) Ron et al., J Biol Chem 1999*
• IRef Intact Interaction: PRKCD — FYN (physical association, anti bait coimmunoprecipitation) Crosby et al., J Biol Chem 2003*