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RELA — TET1
Text-mined interactions from Literome
Liu et al., Acta Pharmacol Sin 2001
(Brain Edema...) :
Tet inhibited neutrophilic recruitment, expression of ICAM-1 mRNA, and activation of
NF-kappaB after brain I/R
Ho et al., Br J Pharmacol 2004
:
We showed that
Tet inhibited
NF-kappaB DNA binding activities induced by various stimuli, including CD28 costimulation ... Since
Tet itself did not
affect NF-kappaB binding to its corresponding DNA sequence, the results suggested that Tet might regulate NF-kappaB upstream signaling molecules
Zhang et al., World J Gastroenterol 2006
(Acute Disease...) :
To investigate the
effect of
Tetrandrine ( Tet ) on LPS induced
NF-kappaB activation and cell injury in pancreatic acinar cells and to explore the mechanism of Tetrandrine preventing LPS induced acinar cell injury
Chen et al., Zhong Xi Yi Jie He Xue Bao 2008
:
To investigate the
effects of
tetrandrine ( Tet ) on
nuclear factor kappaB (NF-kappaB) expression in leukemia cell line K562 and multidrug-resistant K562/A02 cell line ... The activations of NF-kappaB in K562 and K562/A02 cells and the
effects of 1 micromol/L
Tet on
NF-kappaB expression were determined by immunocytochemistry and Western blot assay
Feng et al., Immunol Lett 2008
(Hepatitis, Animal) :
Furthermore,
TET inhibited
NF-kappaB activity, the critical transcriptional factor of the above mentioned inflammatory cytokines, by preventing the activation of IkappaBalpha kinasealpha (IKKalpha) and then inhibiting phosphorylation of IkappaBalpha to stabilize IkappaBalpha in intrahepatic leukocytes