Gene interactions and pathways from curated databases and text-mining

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PPARA — SAA1

Text-mined interactions from Literome

Gervois et al., J Biol Chem 2004 (Acute-Phase Reaction) : PPARalpha prevents the IL-6 induced expression of the positive APR genes fibrinogen-alpha, -beta, -gamma, haptoglobulin, and serum amyloid A and the IL-6 induced suppression of the negative APR gene, major urinary protein
Faty et al., PloS one 2012 (Inflammation) : At the molecular level, SAA represses PPAR?2 , C/EBPa and SREBP-1c gene expression, three transcription factors involved in adipocyte differentiation or lipid synthesis