Gene interactions and pathways from curated databases and text-mining

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CD8B — TLR4

Text-mined interactions from Literome

Palliser et al., J Immunol 2004 : Overall, the results indicate that this Hsfp can activate DC independently of LPS but still requires Tlr4 for an optimal CD8 T cell response
Nadigel et al., Respir Res 2011 (Pulmonary Disease, Chronic Obstructive) : CD8 ( + ) T cells exposed to CSC increased TLR4 and TLR9 levels and increased cytokine production
Heidegger et al., J Immunol 2013 (Salmonella Infections) : We further show that this downregulation is dependent on TLR signaling, and that the TLR activated naive CD8 ( + ) T cells are blocked from entering GALT