Kuster et al., Circulation 2005
(Hypertrophy) :
TRX1 overexpression inhibited the alphaAR stimulated phosphorylation of MEK1/2, ERK1/2 , and p90RSK and prevented cellular hypertrophy, sarcomere reorganization, and protein synthesis ( versus beta-galactosidase )
Yang et al., Microbes Infect 2010
:
Japanese encephalitis virus down-regulates thioredoxin and induces ROS mediated ASK1-ERK/p38 MAPK activation in human promonocyte cells
Song et al., Stem Cells Dev 2011
:
Overexpression of TRX1 and TRX2 increased ERK1/2 phosphorylation, nuclear factor-kappaB activation, and ß-catenin/Tcf promoter activities and inhibited lucine zipper tumor suppressor 2 expression