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FAS — IGF1

Text-mined interactions from Literome

Tu et al., J Immunol 2000 : IGF-1 also significantly inhibited PHA induced Fas expression on cord blood T cells
Fornoni et al., Am J Pathol 2001 : We investigated whether Bcl-xL and Fas/Fas-ligand were regulated by CsA in cultured podocytes and whether CsA induced apoptosis was prevented by HGF or IGF-I
Casellas et al., Diabetes 2006 (Diabetes Mellitus, Experimental...) : IGF-I expression in IFN-beta expressing beta-cells of double-transgenic mice reduced beta(2)-microglobulin, blocked Fas expression, and counteracted islet infiltration
Himpe et al., J Endocrinol 2008 : IGF1 did not affect Fas expression or activation by anti-Fas of caspase-8, but inhibited the depolarization of the mitochondrial membrane
Misra et al., Biochem J 1994 : We have investigated insulin-like growth factor-I (IGF-I) regulation of FAS by transfecting into 3T3-L1 fibroblasts chimeric genes comprising the 5'-flanking region of the FAS gene linked to a luciferase ( LUC ) reporter gene ... The half-maximal effect of IGF-I on FAS promoter activity was observed at 3 nM and a maximal effect was reached at 10 nM ... Furthermore, sequences responsible for IGF-I regulation of the FAS gene are located within the proximal promoter between nucleotides -67 and -19 of the FAS gene
Kawakami et al., Biochem Biophys Res Commun 1998 (Leukemia, Erythroblastic, Acute) : Both Fas expression and the degree of anti-Fas IgM induced apoptosis of human osteoblasts was also augmented by IGF-I ... Furthermore, the cytotoxicity of Fas ligand (FasL) cDNA transformants against human osteoblasts was increased when IGF-I stimulated osteoblasts were used as target cells, indicating that stimulation of IGF-I increased functional Fas expression on human osteoblasts as well as their proliferation