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CCNE2 — CDKN1A
Pathways - manually collected, often from reviews:
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Bind Interaction:
CDKN1A
—
CCNE2
Ramachandran et al., Science 2004
-
IRef Bind_translation Interaction:
CDKN1A
—
CCNE2
(array technology)
Ramachandran et al., Science 2004
-
IRef Biogrid Interaction:
CDKN1A
—
CCNE2
(physical association, affinity chromatography technology)
Lauper et al., Oncogene 1998*
-
IRef Biogrid Interaction:
CDKN1A
—
CCNE2
(direct interaction, two hybrid)
Zariwala et al., Oncogene 1998
-
IRef Biogrid Interaction:
CDKN1A
—
CCNE2
(direct interaction, pull down)
Ramachandran et al., Science 2004
-
IRef Hprd Interaction:
CDKN1A
—
CCNE2
(two hybrid)
Ramachandran et al., Science 2004, Zariwala et al., Oncogene 1998
-
IRef Intact Interaction:
Complex of 18 proteins
(association, tandem affinity purification)
Varjosalo et al., Cell reports 2013
-
IRef Intact Interaction:
Complex of 30 proteins
(association, tandem affinity purification)
Varjosalo et al., Nat Methods 2013
-
IRef Intact Interaction:
CDKN1A
—
CCNE2
(direct interaction, protein array)
Ramachandran et al., Science 2004
-
IRef Intact Interaction:
CDKN1A
—
CCNE2
(physical association, two hybrid)
Zariwala et al., Oncogene 1998
-
IRef Ophid Interaction:
CDKN1A
—
CCNE2
(aggregation, interologs mapping)
Brown et al., Bioinformatics 2005
Text-mined interactions from Literome
Ariazi et al., Cancer Res 1999
(Mammary Neoplasms, Animal) :
RNA expression studies, based on a multiplexed-nuclease protection assay, demonstrated that cell cycle- and apoptosis related genes were differentially expressed within 48 h of POH treatment ;
p21 ( Cip1/WAF1 ), bax, bad, and annexin I were
induced ;
cyclin E and cyclin dependent kinase 2 were repressed ; and bcl-2 and p53 were unchanged
Li et al., J Biol Chem 2002
:
p21 binds to and
inhibits both the DNA synthesis regulator proliferating cell nuclear antigen and
cyclin A/E-CDK2 complexes