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PTGS2 — SRGN

Text-mined interactions from Literome

Jiang et al., Zhongguo Zhong Xi Yi Jie He Za Zhi 2008 (Disease Models, Animal...) : To investigate the effects of Propyl Gallate (PrG) on serum inflammatory factors and protein expression of cyclooxygenase-2 (COX-2) and intercellular adhesion molecule-1 ( ICAM-1 ) in ischemic myocardium of rats with acute myocardial infarction ( AMI ) ... PrG ( 40 mg x kg ( -1 ) d ( -1 ) ) could decrease the serum level of inflammatory factor TNF-alpha, and slightly inhibit COX-2 and ICAM-1 protein expression in ischemic myocardium of AMI rats
Jadhav et al., Phytomedicine 2013 : Wattakaka volubilis steroidal glycoside mixture ( WVSM ) and PPG ( 1-50µM ) significantly inhibited the COX-2 and iNOS enzymes resulting in low levels of PGE2 and NO in LPS induced RAW 264.7 macrophage cells