◀ Back to IL8
IL8 — MUC5AC
Text-mined interactions from Literome
Kikuchi et al., Am J Respir Cell Mol Biol 2006
(Asthma...) :
The
TBM of eosinophils in
response to
IL-8 was evaluated in the presence or absence of neutrophils using the chambers with a Matrigel coated transwell insert ... Neither
IL-8 alone nor the presence of neutrophils alone
induced the
TBM of eosinophils
Bautista et al., J Immunol 2009
:
In this study, the
effects of
IL-8 on expression of two major airway mucin genes,
MUC5AC and MUC5B, were evaluated ...
IL-8 also
increased MUC5AC and MUC5B mRNA levels in primary normal differentiated human bronchial epithelial cells, with a high concentration of IL-8 required to increase MUC5B mRNA levels ...
IL-8 did not transcriptionally up-regulate MUC5AC gene expression, but rather
increased the stability of the
MUC5AC transcript, suggesting regulation at the posttranscriptional level
Mata et al., PloS one 2013
(Metaplasia...) :
RNO inhibited RSV infection of WD-HBE, prevented the loss of ciliated cells and markers, reduced the increase of
MUC5AC and CLCA1 and
inhibited the increase of IL-13, IL-6,
IL-8 , TNFa and ICAM-1