Gene interactions and pathways from curated databases and text-mining

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IL8 — MUC5AC

Text-mined interactions from Literome

Kikuchi et al., Am J Respir Cell Mol Biol 2006 (Asthma...) : The TBM of eosinophils in response to IL-8 was evaluated in the presence or absence of neutrophils using the chambers with a Matrigel coated transwell insert ... Neither IL-8 alone nor the presence of neutrophils alone induced the TBM of eosinophils
Bautista et al., J Immunol 2009 : In this study, the effects of IL-8 on expression of two major airway mucin genes, MUC5AC and MUC5B, were evaluated ... IL-8 also increased MUC5AC and MUC5B mRNA levels in primary normal differentiated human bronchial epithelial cells, with a high concentration of IL-8 required to increase MUC5B mRNA levels ... IL-8 did not transcriptionally up-regulate MUC5AC gene expression, but rather increased the stability of the MUC5AC transcript, suggesting regulation at the posttranscriptional level
Mata et al., PloS one 2013 (Metaplasia...) : RNO inhibited RSV infection of WD-HBE, prevented the loss of ciliated cells and markers, reduced the increase of MUC5AC and CLCA1 and inhibited the increase of IL-13, IL-6, IL-8 , TNFa and ICAM-1