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EGF — ESR2

Text-mined interactions from Literome

Apostolakis et al., Mol Endocrinol 2000 : The potent mitogen epidermal growth factor (EGF) activates estrogen receptor ( ER ) -dependent transcription in cultured cells in the absence of exogenous E
Biswas et al., Proc Natl Acad Sci U S A 2001 (Breast Neoplasms...) : The effect of a kinase inhibitor Go6796 on growth of epidermal growth factor (EGF) stimulated estrogen receptor negative ( ER- ) breast cancer cells in vivo and role of nuclear factor kappa B (NF-kappaB) on tumorogenesis have been investigated
Li et al., Endocrinology 2006 (MAP Kinase Signaling System) : The effect is mediated by estrogen receptor-alpha and involves in part the EGF-EGF receptor and ERK-MAPK cascades as proximal signaling networks and the CK2 and Rho associated kinase regulated myosin heavy chain phosphatase as terminal effectors
Jia et al., Nan Fang Yi Ke Da Xue Xue Bao 2006 (Prostatic Hyperplasia) : To investigate the effects of epidermal growth factor (EGF) on estrogen receptor ( ER ) and androgen receptor (AR) in mouse prostate cells and explore the putative role of EGF in prostatic hyperplasia
Berno et al., PloS one 2008 : Activation of estrogen receptor-alpha by E2 or EGF induces temporally distinct patterns of large-scale chromatin modification and mRNA transcription
Shen et al., Biomed Pharmacother 2010 (Carcinoma, Non-Small-Cell Lung...) : Additionally, EGFR and ERbeta expression was down-regulated in response to estrogen and EGF , respectively, but up-regulated in response to tamoxifen and genfitib, respectively
Galand et al., Endocrinology 1996 : Considering reports from the literature showing that EGF can directly induce the phosphorylated active form of the estrogen receptor , we speculate that this might implicate its action on cGMP, with the latter then intervening as cofactor of the involved phosphokinase ( s )
Bunone et al., EMBO J 1996 : Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation
Curtis et al., Proc Natl Acad Sci U S A 1996 : These studies have suggested a `` cross-talk '' model in which EGF receptor (EGF-R) signaling results in activation of nuclear estrogen receptor ( ER ) and its target genes in an estrogen independent manner
Damien et al., J Bone Miner Res 1998 : That both ICI 182,780 and tamoxifen, which in other tissues act as estrogen antagonists, should reduce osteoblast proliferation stimulated by 17beta-estradiol and EGF, but not that by FGF or the IGFs, was expected since the mitogenic effects of estrogen and EGF involve the estrogen receptor , whereas those of FGF and the IGFs do not