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AREGB — EGF

Text-mined interactions from Literome

Culouscou et al., Growth Factors 1992 (Colonic Neoplasms) : Although CRDGF was shown to inhibit the binding of epidermal growth factor (EGF) to its receptor, several lines of evidence suggested that it was distinct from EGF or transforming growth factor-alpha ( TGF-alpha )
Culouscou et al., Int J Cancer 1988 (Carcinoma...) : In contrast, EGF binding to any of the human colorectal cancer cell lines tested, i.e., HT-29, HT-29 ( clone D4 ), HRT-18 or CAL-14, remains unaltered in the presence of exogenous CRDGF ... Scatchard analysis of EGF binding on suramin treated HT-29 cells shows that CRDGF inhibits EGF binding by decreasing EGF receptor affinity, as previously observed with the non-colonic cell types
Stoll et al., J Clin Invest 1997 : Amphiregulin and heparin binding EGF-like growth factor ( HB-EGF ) transcripts were rapidly and markedly induced , whereas EGF and TGF-alpha mRNAs were undetectable or only slightly increased