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BACE1 — PPARA
Text-mined interactions from Literome
Zhao et al., PloS one 2011
(Alzheimer Disease...) :
Use of the thiazolidinedione peroxisome proliferator activated receptor gamma ( PPAR? ) agonist rosiglitazone, the irreversible PPAR? antagonist GW9662, and overexpressing PPAR? suggests that the NPD1 mediated down-regulation of
BACE1 and Aß42 peptide release is
PPAR? dependent
Chen et al., Eur J Pharmacol 2012
(Alzheimer Disease) :
Ginsenoside Rg1 attenuates ß-amyloid generation via suppressing
PPAR? regulated
BACE1 activity in N2a-APP695 cells