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CD34 — IL15

Text-mined interactions from Literome

Drouet et al., Stem Cells 2001 : We showed in a nonhuman primate model of autologous peripheral blood stem and progenitor cell transplantation that cell cycle activation of CD34 ( + ) cells in the presence of stem cell factor + FLT3-ligand + thrombopoietin + interleukin 3 ( six days of culture ) which induced G1 and S/G2/M cell amplification ( G0 : 6.1 % +/- 2.8 % ; G0/G1 : 64.2 % +/- 7.2 % ; S/G2/M : 30.4 % +/- 7.3 % respectively of expanded CD34 ( + ) cells on average ) resulted in the acceleration of short-term granulocyte recovery
Yu et al., Blood 1998 : Interleukin-15 (IL-15) is produced by human bone marrow ( BM ) stromal cells and can induce CD34 ( + ) hematopoietic progenitor cells ( HPCs ) to differentiate into CD56 ( + ) CD3 ( - ) natural killer ( NK ) cells in the absence of stromal cells