Gene interactions and pathways from curated databases and text-mining

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IFNG — TAC3

Text-mined interactions from Literome

Hosoda et al., J Immunol 1989 (Leukemia, Eosinophilic, Acute) : Whereas IFN-gamma up-regulated the receptor expression of IL-2R/Tac , IL-4 did not
Vilcek et al., J Immunol 1985 : Monoclonal antibody anti-Tac , specific for an epitope associated with the IL 2 receptor (IL 2 R), inhibited IFN-gamma induction by exogenous IL 2 less strongly than induction by phytohemagglutinin ( PHA ) or concanavalin A ( Con A )
Reem et al., Science 1984 : Anti-Tac , a monoclonal antibody known to prevent the binding of IL-2 to its receptor without inhibiting IL-2 synthesis, down-regulated the expression of the receptor and partially inhibited synthesis of IFN-gamma
Blum et al., J Immunol 1993 (Granuloma...) : Specific NK-1 receptor antagonists blocked all tachykinin induced , IFN-gamma secretion