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IFNG — TAC3
Text-mined interactions from Literome
Hosoda et al., J Immunol 1989
(Leukemia, Eosinophilic, Acute) :
Whereas
IFN-gamma up-regulated the receptor expression of
IL-2R/Tac , IL-4 did not
Vilcek et al., J Immunol 1985
:
Monoclonal antibody
anti-Tac , specific for an epitope associated with the IL 2 receptor (IL 2 R),
inhibited IFN-gamma induction by exogenous IL 2 less strongly than induction by phytohemagglutinin ( PHA ) or concanavalin A ( Con A )
Reem et al., Science 1984
:
Anti-Tac , a monoclonal antibody known to prevent the binding of IL-2 to its receptor without inhibiting IL-2 synthesis, down-regulated the expression of the receptor and partially
inhibited synthesis of
IFN-gamma
Blum et al., J Immunol 1993
(Granuloma...) :
Specific NK-1 receptor antagonists blocked all
tachykinin induced ,
IFN-gamma secretion