Koide et al., J Bone Miner Res 2003
:
However, OIP-1/hSca did not affect NF-kappaB activation in these cells
Park et al., Biochem Biophys Res Commun 2007
(Embryo Loss) :
TRIP also directly interacts with the familial cylindromatosis tumor suppressor gene ( CYLD ) and negatively regulates NF-kappaB activation in vitro
Chastre et al., FASEB J 2009
(Colorectal Neoplasms) :
The TRIP6Stop473 mutant, which lacks the PDZ binding motif, was still able to increase NF-kappaB and Akt activities but did not promote invasiveness or interfere with cell-cell aggregation
Lee et al., J Exp Med 1997
:
When associated, TRIP inhibits the TRAF2 mediated NF-kappaB activation that is required for cell activation and also for protection against apoptosis