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CCR7 — NFKB1

Text-mined interactions from Literome

Höpken et al., Blood 2002 (Hodgkin Disease...) : CCR7 up-regulation was mediated by constitutive NF-kappaB activity
Liu et al., Mol Immunol 2007 : Further studies show that the triptolide mediated inhibitory effects of LPS induced activation of phosphatidylinositol-3 kinase (PI3-K)/Akt and nuclear NF-kappaB activation are involved in down-regulation of COX-2 and CCR7 expression resulting in impaired migration to secondary lymphoid organs of DC
Mburu et al., Immunol Res 2006 (Carcinoma, Squamous Cell...) : Based on our recent findings, the induction of CCR7 expression and the sustenance of the autocrine signaling pathway have been shown to be regulated by NF-kappaB , similar to several types of immune cells
Pan et al., J Biol Chem 2009 : Tubocapsanolide A inhibits transforming growth factor-beta activating kinase 1 to suppress NF-kappaB induced CCR7 ... A bioactive withanolide tubocapsanolide A ( Tubo A ) suppressed NF-kappaB mediated CCR7 expression in breast cancer cells and attenuated their migration toward lymphatic endothelial cells ... We conclude that Tubo A inhibits TAK1 to repress NF-kappaB induced CCR7 expression in breast cancer cells and suggest that Tubo A may be useful for the prevention of lymphatic invasion of breast cancer cells
Larangé et al., J Leukoc Biol 2009 : We found that upon TLR7 and TLR8 activation, JNK and NF-kappaB positively regulated the expression of CCR7 , CD86, CD83, and CD40 and the production of IL-6 and IL-12p40
Rehm et al., Int J Cancer 2009 (Lymphoma, Large B-Cell, Diffuse...) : Given the role of NF-kappaB in the transcriptional activation of CCR7 , we identified the involvement of the noncanonical activation pathway in MLBCLs. MLBCLs exhibit a diagnostic chemokine receptor profile that is instrumental in the discrimination from diffuse large B-cell lymphoma not otherwise specified and classical Hodgkin lymphoma