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RELA — SOD3

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Shi et al., Mol Cell Biochem 1999 : This activation of NF-kappaB was decreased by a metal chelator, diethylene triaminepentaacetic acid or a H2O2 scavenger, catalase, but was increased by superoxide dismutase
Wang et al., Ann Clin Lab Sci 1999 : Superoxide dismutase ( SOD ) , but not catalase or sodium formate, inhibited this NF-kappaB activation, suggesting that O2*- rather than H2O2 or *OH, radicals play the most critical role in this induction
Darville et al., Endocrinology 2000 : NF-kappaB is required for cytokine induced manganese superoxide dismutase expression in insulin producing cells
Ye et al., Ann Clin Lab Sci 2000 : Exogenous superoxide dismutase ( SOD ) enhanced the NF-kappaB activation by PMA, while catalase blocked it
Jan et al., J Virol 2000 (Neuroblastoma) : The finding that AACOCF ( 3 ) and SOD significantly block activation of NF-kappaB suggests that this activation is derived from the AA-superoxide anion pathway
Kim et al., J Korean Med Sci 2000 (Acute Disease...) : Present study aims to investigate whether neutrophils primed by 4beta-phorbol 12beta-myristate 13alpha-acetate ( PMA ) affect the productions of H2O2 and lipid peroxide (LPO), NF-kappaB activation and cytokine production in pancreatic acinar cells, and whether these alterations were inhibited by N-acetylcysteine (NAC) and superoxide dismutase ( SOD )
Seo et al., Pharmacology 2002 : Small-molecule antioxidants and SOD inhibited NF-kappaB activation and cytokine production in acinar cells caused by PMA primed neutrophils
Fan et al., J Biol Chem 2003 (Anoxia) : Overexpression of glutathione peroxidase-1 or catalase, but not Mn-SOD or Cu, Zn-SOD, significantly reduced both NF kappa B activation and tyrosine phosphorylation of I kappa B alpha
Casciati et al., J Neurochem 2002 (Amyotrophic Lateral Sclerosis...) : In this paper, we report a calcineurin dependent activation of nuclear factor-kappaB (NF-kappaB) induced by the expression of familial amyotrophic lateral sclerosis ( fALS ) -SOD1s in human neuroblastoma cell lines
Yang et al., Mol Ther 2003 (Myocardial Reperfusion Injury...) : These findings support the notion that both mitochondrial and cytoplasmic derived SOD induce changes in AP-1 and NF kappa B activity, creating an antiapoptotic microenvironment within cardiomyocytes that affords protection following I/R injury
Cardoso et al., Free radical research 2003 (Alzheimer Disease) : We observed that the NF-kB inhibitor, PDTC, prevented SOD overexpression after A beta treatment
Kaneko et al., Biol Pharm Bull 2004 : Manganese superoxide dismutase is induced by endoplasmic reticulum stress through IRE1 mediated nuclear factor (NF)-kappaB and AP-1 activation
Yune et al., J Neurotrauma 2004 (Spinal Cord Injuries) : Manganese superoxide dismutase induced by TNF-beta is regulated transcriptionally by NF-kappaB after spinal cord injury in rats
Song et al., J Cereb Blood Flow Metab 2005 (Brain Ischemia) : However, SOD 1 prevented NF-kappaB activation, and phosphorylation and degradation of IkappaBalpha after tFCI
Rui et al., FASEB J 2005 (Inflammation) : NFkappaB and AP-1 differentially contribute to the induction of Mn-SOD and eNOS during the development of oxidant tolerance ... In this model, nuclear translocation of both NF-kappaB and AP-1 is required for induction of Mn-SOD , while nuclear translocation of AP-1, but not NF-kappaB, is a prerequisite for induction of eNOS
Gomez-Cabrera et al., Br J Nutr 2006 : In animal models, we previously showed that NF-kappaB activation induced by exhaustive physical exercise leads to an increase in the expression of superoxide dismutase , an enzyme involved in antioxidant defence
Yang et al., Chin J Integr Med 2007 (Learning Disorders...) : TCA could improve A beta 25-35 induced dysfunction of learning and memory in rats, and its protective mechanism is associated with its actions in decreasing MDA level, increasing Mn-SOD activity and inhibiting the expression of NF-kappa B in cerebral cortex
Viña et al., Biol Chem 2008 : Activation of NF-kappa B by estrogens subsequently activates the expression of Mn-SOD and GPx, but genistein is only capable of activating Mn-SOD expression
Kiningham et al., Free Radic Biol Med 2008 (Neuroblastoma) : All-trans-retinoic acid induces manganese superoxide dismutase in human neuroblastoma through NF-kappaB
Xu et al., Planta Med 2008 (Infarction, Middle Cerebral Artery...) : Pre-treatment with isosteviol reduced infarct volume, ameliorated cell death and infiltration of neutrocytes, improved neuro-locomotor activity, increased SOD activity, induced Bcl-2, suppressed lipid superoxidation and the expression of NF-kappaB , and therefore retarded necrosis and apoptosis of neurons and inflammation
Zhang et al., Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 2008 (Disease Models, Animal) : Compared with control group, SOD activity in LPS group decreased at different time points significantly ( P < 0.05 or P < 0.01 ), but MPO activity, MDA content and the expression of NF-kappaB increased obviously ( P < 0.05 or P < 0.01 ) ; the administration of MT and DEX could mitigate above values significantly ( P < 0.05 or P < 0.01 )
Lee et al., Exp Mol Med 2009 : Tat-SOD inhibited LPS induced NF-kappaB DNA binding activity, IkappaBalpha degradation and activation of MAP kinases
Shan et al., J Biomed Biotechnol 2009 (Brain Injuries...) : Interestingly, we found, PSPC decreased the expression level of glial fibrillary acidic protein (GFAP), inducible nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX-2), inhibited nuclear translocation of nuclear factor-kappaB (NF-kappaB) , increased the activity of copper/zinc superoxide dismutase ( Cu/Zn-SOD ) and catalase (CAT), and reduced the content of malondialdehyde ( MDA ), respectively
Lee et al., Mol Cells 2010 (MAP Kinase Signaling System) : Furthermore, cell-permeable SOD inhibited LPS induced NF-kappaB DNA binding activity and activation of MAP kinases including ERK, JNK, and p38 in BV-2 cells
Das et al., Mol Cell Biochem 1995 (Adenocarcinoma...) : TNF alpha and IL-1 each can activate NF-kappa B and induce gene expression of manganese superoxide dismutase ( MnSOD ), a mitochondrial matrix enzyme which can provide critical protection against hyperoxic lung injury
Weiss et al., J Immunol 1997 : TNFR80 induces no cytotoxicity on its own, but is functional in these transfectants, as selective stimulation activates nuclear factor-kappaB (NF-kappaB) and induces NF-kappaB dependent cellular responses ( IL-6 and manganese superoxide dismutase )
Marumo et al., Circulation 1997 : In contrast, superoxide dismutase did not inhibit the interleukin-1beta induced NF-kappaB activation
Schmidt et al., Chem Biol 1995 (Second Messenger Systems) : In contrast, stable overexpression of cytoplasmic Cu/Zn dependent superoxide dismutase ( SOD ) , which enhances the production of H2O2 from superoxide, potentiated NF-kappa B activation
Borrello et al., Arch Biochem Biophys 1997 : NF kappa B-independent transcriptional induction of the human manganous superoxide dismutase gene
Manna et al., J Biol Chem 1998 : Besides TNF, phorbol ester-, okadaic acid-, ceramide-, and lipopolysaccharide induced activation of NF-kappaB was blocked by Mn-SOD , indicating a common pathway of activation