Gene interactions and pathways from curated databases and text-mining

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CDKN1A — NABP2

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Xu et al., Oncogene 2011 (Carcinoma, Hepatocellular...) : Here, we present evidence that hSSB1 directly binds p21 and this interaction may prevent p21 from ubiquitin mediated degradation
Xu et al., Cell Res 2013 : Furthermore, hSSB1 also associates with the acetyltransferase p300 and is required for efficient transcriptional activation of the p53 target gene p21 by affecting the acetylation of p53 at lysine382 ... Collectively, our results indicate that hSSB1 may regulate DNA damage checkpoints by positively modulating p53 and its downstream target p21