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CDKN1A — NABP2
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Xu et al., Oncogene 2011
(Carcinoma, Hepatocellular...) :
Here, we present evidence that
hSSB1 directly binds p21 and this interaction may
prevent p21 from ubiquitin mediated degradation
Xu et al., Cell Res 2013
:
Furthermore,
hSSB1 also associates with the acetyltransferase p300 and is
required for efficient transcriptional activation of the p53 target gene
p21 by affecting the acetylation of p53 at lysine382 ... Collectively, our results indicate that
hSSB1 may
regulate DNA damage checkpoints by positively modulating p53 and its downstream target
p21