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HDAC8 — RELA

Text-mined interactions from Literome

Foss et al., Leukemia & lymphoma 2003 (Lymphoma, T-Cell, Cutaneous) : Other novel agents include the interleukin (IL)-2 fusion toxin ( ONTAK ), pentostatin ( a potent adenosine deaminase inhibitor ), histone deacetylase inhibitors such as depsipeptide, NF-kappaB inhibitors , cytokine receptor antagonists, immunomodulatory therapies and allogeneic stem cell therapy
Glauben et al., Gut 2008 (Colitis...) : As for potential mechanisms of ITF2357 action, increased acetylation of histone 3, reduced production of IFN gamma and enhanced apoptosis in lamina propria mononuclear cells were found to accompany a histone deacetylase dependent activation of NF-kappaB
Hayes et al., Eur J Nutr 2008 (Neoplasms) : In particular, their abilities to induce cytoprotective genes, mediated by the Nrf2 ( NF-E2 related factor 2 ) and AhR ( arylhydrocarbon receptor ) transcription factors, and their abilities to repress NF-kappaB ( nuclear factor-kappaB ) activity, inhibit histone deacetylase , and inhibit cytochrome P450 are outlined