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LEP — NFKBIA

Text-mined interactions from Literome

Mattace Raso et al., Neurosci Lett 2006 (Glioma) : The role of NF-kappaB was also confirmed by time course studies on degradation of IkappaB-alpha, which began to degrade 5 min after treatment with leptin and returned to basal level after 30-60 min. Pre-incubation of cells with MG132 inhibited leptin induced IkappaB-alpha degradation
Tang et al., J Immunol 2007 : Stimulation of microglia with leptin activated IkappaB kinase alpha/IkappaB kinase beta, IkappaBalpha phosphorylation, IkappaBalpha degradation, p65 phosphorylation at Ser ( 276 ), p65 and p50 translocation from the cytosol to the nucleus, and kappaB-luciferase activity