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UCSC Genome Browser Gene Interaction Graph
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Gene interactions and pathways from curated databases and text-mining
◀ Back to RAP1A
RAP1A — SIPA1
Pathways - manually collected, often from reviews:
KEGG Leukocyte transendothelial migration :
RAP1A/RAP1B
→
SIPA1
(protein-protein, inhibition)
NCI Pathway Database PDGFR-beta signaling pathway :
afadin/SPA-1 complex (MLLT4-SIPA1)
→
RAP1/GTP/afadin complex (RAP1B_RAP1A-MLLT4)
(modification, collaborate)
Takahashi et al., Genes Cells 2008 , Miyata et al., J Biol Chem 2009
Evidence: mutant phenotype, assay, physical interaction, other species
NCI Pathway Database PDGFR-beta signaling pathway :
afadin/SPA-1 complex (MLLT4-SIPA1)
→
RAP1/GTP complex (RAP1B_RAP1A)
(modification, collaborate)
Takahashi et al., Genes Cells 2008 , Miyata et al., J Biol Chem 2009
Evidence: mutant phenotype, assay, physical interaction, other species
NCI Pathway Database PDGFR-beta signaling pathway :
RAP1/GTP/afadin complex (RAP1B_RAP1A-MLLT4)
→
SPA-1 (SIPA1)
(modification, collaborate)
Takahashi et al., Genes Cells 2008 , Miyata et al., J Biol Chem 2009
Evidence: mutant phenotype, assay, physical interaction, other species
NCI Pathway Database PDGFR-beta signaling pathway :
SPA-1 (SIPA1)
→
RAP1/GTP complex (RAP1B_RAP1A)
(modification, collaborate)
Takahashi et al., Genes Cells 2008 , Miyata et al., J Biol Chem 2009
Evidence: mutant phenotype, assay, physical interaction, other species
NCI Pathway Database PDGFR-beta signaling pathway :
SPA-1 (SIPA1)
→
RAP1/GTP complex (RAP1B_RAP1A)
(modification, activates)
Miyata et al., J Biol Chem 2009
Evidence: mutant phenotype, other species
Reactome Reaction :
RAP1A
→
SIPA1
(reaction)
Schultess et al., Blood 2005 * , Polakis et al., Proc Natl Acad Sci U S A 1991 * , Kurachi et al., J Biol Chem 1997 *