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CSF3 — NOS3
Text-mined interactions from Literome
Stephan et al., Int J Tissue React 1999
:
However, both IL-1 beta and G-CSF caused a significant increase ( p < 0.05 ) in nitrite levels at 48 h. NG-L-arginine-methyl-ester was used to inhibit nitrite production
induced by
G-CSF and this implicated
nitric oxide synthase activity
Hu et al., International journal of molecular sciences 2013
:
Further research revealed that
G-CSF promoted the upregulation of endothelin-1 (ET-1) and the downregulation of
endothelial nitric oxide synthase (eNOS) of thoracic aortae induced by a high-fat diet ... In vitro, the
effects of
G-CSF on expression of ET-1 and
eNOS in cultured ECs were consistent with those in vivo
Squadrito et al., Br J Pharmacol 1997
(Mesenteric Vascular Occlusion...) :
Finally rh
G-CSF potently
inhibited the activity of inducible
nitric oxide synthase in peritoneal macrophages activated with endotoxin
Squadrito et al., Int J Microcirc Clin Exp 1997
(Acute Disease...) :
Finally, rh
G-CSF inhibited the activity of inducible
nitric oxide synthase in peritoneal macrophages activated with endotoxin
Hoffmann et al., Eur J Pharmacol 1998
:
Granulocyte-colony stimulating factor inhibits inducible
nitric oxide synthase gene expression in pulmonary epithelial cells in vitro ... We show that
G-CSF suppresses interferon-gamma/tumor necrosis factor-alpha (TNF-alpha)
induced inducible
nitric oxide synthase gene expression detected as inducible nitric oxide synthase cDNA ( cDNA concentration was 633 +/- 38 amol/microg total RNA following 24 h incubation with 100 U/ml interferon-gamma/500 U/ml TNF-alpha, and 440 +/- 14 amol/microg total RNA following 24 h incubation with 250 U/ml G-CSF +/- 100 U/ml interferon-gamma/500 U/ml TNF-alpha, respectively )