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EPHB4 — RHOA
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Moeller et al., J Biol Chem 2006
:
Finally,
EphB mediated
RhoA activation is disrupted by FAK knock-down
Ogawa et al., J Cell Sci 2006
:
Interestingly, we found that
EphB signaling
induces RhoA activation and Rac1 inactivation as well as cell retraction, enlargement of focal adhesions and prominent stress fibers in primary cultures of medullary tubule cells
Yang et al., J Biol Chem 2006
(Melanoma) :
Activation of
EphB4 receptor with its ligand ephrin-B2-Fc enhances the migratory ability of melanoma cells and
increases RhoA activity, whereas inhibiting EphB receptor forward signaling decreases RhoA activity