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GAB1 — MAPK10

Text-mined interactions from Literome

Cunnick et al., J Biol Chem 2001 : Thus, physical association of activated SHP2 with Gab1 is necessary and sufficient to mediate the ERK mitogen activated protein kinase activation
Cai et al., J Cell Biol 2002 (MAP Kinase Signaling System) : Gab1 and SHP-2 promote Ras/MAPK regulation of epidermal growth and differentiation
Chen et al., J Biol Chem 2002 : Incubation of cells with the specific EGFR inhibitor AG4178 blocked MbetaCD induced phosphorylation of EGFR, SHC, phospholipase C-gamma, and Gab-1 as well as MAPK activation
Lamothe et al., Mol Cell Biol 2004 : We demonstrate that Gab1 is essential for FGF1 stimulation of both PI 3-kinase and the antiapoptotic protein kinase Akt, while FGF1 induced mitogen activated protein kinase ( MAPK ) stimulation is not affected by Gab1 deficiency
Eulenfeld et al., J Cell Sci 2009 : Instead, additional MAPK dependent phosphorylation of Ser551 in Gab1 is crucial for the recruitment of Gab1 to the plasma membrane