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BRCA1 — JUN
Pathways - manually collected, often from reviews:
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Bind Interaction:
BRCA1
—
JUN
Hu et al., Genes Dev 2002*
-
IRef Bind_translation Interaction:
BRCA1
—
JUN
(coimmunoprecipitation)
Hu et al., Genes Dev 2002*
-
IRef Bind_translation Interaction:
BRCA1
—
JUN
(affinity chromatography technology)
Hu et al., Genes Dev 2002*
-
IRef Biogrid Interaction:
BRCA1
—
JUN
(physical association, affinity chromatography technology)
Hu et al., Genes Dev 2002*
-
IRef Biogrid Interaction:
BRCA1
—
JUN
(direct interaction, pull down)
Hu et al., Genes Dev 2002*
-
IRef Dip Interaction:
BRCA1
—
JUN
(physical association, affinity chromatography technology)
Hu et al., Genes Dev 2002*
-
IRef Dip Interaction:
BRCA1
—
JUN
(physical association, coimmunoprecipitation)
Hu et al., Genes Dev 2002*
-
IRef Hprd Interaction:
BRCA1
—
JUN
(in vitro)
Hu et al., Genes Dev 2002*
-
IRef Hprd Interaction:
BRCA1
—
JUN
(in vivo)
Hu et al., Genes Dev 2002*
-
IRef Ophid Interaction:
BRCA1
—
JUN
(aggregation, interologs mapping)
Brown et al., Bioinformatics 2005
Text-mined interactions from Literome
Jin et al., Oncogene 2000
(Adenocarcinoma...) :
BRCA1 did not
induce the
c-Jun and c-fos promoters, which rules out a general effect of BRCA1 on other immediate-responsive genes
Nakuci et al., Exp Cell Res 2006
(Breast Neoplasms) :
( 4 )
BRCA1-IRIS activation of
JNK/c-Jun/AP1 appears to account for this, because in cells that were depleted from BRCA1-IRIS, JNK remained inactive
Zhou et al., Mol Cancer Res 2013
(Ovarian Neoplasms) :
Microenvironmental
Regulation of
BRCA1 Gene Expression by
c-Jun and Fra2 in Premalignant Human Ovarian Surface Epithelial Cells