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APC — IL10

Text-mined interactions from Literome

Zhong et al., Anesthesiology 2004 (Myocardial Infarction...) : APC with sevoflurane attenuated NF-kappaB activation and reduced the expression of tumor necrosis factor alpha, interleukin 1, intercellular adhesion molecule 1, and inducible nitric oxide synthase
Mehrotra et al., Immunology 2004 (Melanoma) : Among the various microenvironmental factors, interleukin-10 (IL-10) exhibits a potent immunosuppressive effect on antigen presenting cells (APC)
Tsukahara et al., Int Immunol 2005 : The present results indicated that CD80 and CD86 play a critical role in induction of ACAID, possibly by co-stimulating expansion and IL-10 production of regulatory T cells in response to TGF-beta conditioned APC
Kryczek et al., J Immunol 2006 : Further, APC derived, rather than Treg cell derived, IL-10 is responsible for APC B7-H4 induction
Fiorentino et al., J Immunol 1991 : By preincubating APC with IL-10, we demonstrate that IL-10 acts principally on APC to inhibit IFN-gamma production by Th1 clones
Vogt et al., Microbes Infect 2008 (Chagas Disease) : Lymph node TCRBV9+ T cells secreted IFN-gamma and IL-10 , but not IL-4, upon stimulation with TcAg in the presence of APC
Xin et al., Mol Immunol 2008 (Leishmaniasis, Cutaneous) : La amastigote infected DCs were less mature and less potent antigen presenting cells (APC) than their promastigote infected counterparts, as judged by the lower expression of CD40 and CD83, suppressed cytokine expression ( IL-12p40 and IL-10 ), reduced effectiveness for priming CD4+ T cells from naïve or infected mice
Naundorf et al., Eur J Immunol 2009 : In contrast, IL-10 did not affect anti-CD3/anti-CD28 induced IL-17 production from memory T cells even in the presence of APC
Hisatsune et al., Cell Immunol 1994 : In response to autologous APC , both D2 and 4B4 produced considerable amounts of interferon-gamma and a low but significant level of IL-10
Frei et al., J Immunol 1994 : In the present study we have examined the effect of IL-10 on different APC obtained from the central nervous system
van der Veen et al., J Neuroimmunol 1993 : The addition of recombinant IL-4 ( rIL-4 ) and rIL-10 confirmed that inhibition of Th1 proliferation was due to secretion of IL-10 by the Th2 clone and its subsequent effects on APC
Flores Villanueva et al., J Immunol 1993 (Hypersensitivity, Delayed) : IL-10 produced in schistosome infected individuals may play a role in the generation of APC , such as macrophages in schistosomal egg granulomas, unable to efficiently stimulate, but capable of inducing a state of anergy/unresponsiveness in Th-1 lymphocytes
Del Prete et al., J Immunol 1993 : Preincubation of APC, but not of clonal T blasts, with h-IL-10 resulted in the inhibition of Ag-induced proliferation of both Th1 and Th2 clones, supporting the view that h-IL-10 primarily affects APC