Gene interactions and pathways from curated databases and text-mining

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CCL28 — TP53

Text-mined interactions from Literome

Lin et al., Food Chem Toxicol 2007 (Colonic Neoplasms) : As for apoptosis, MEC may induce upregulation of p53 and downregulation of Bcl-2, thus causing the release of cytochrome C from mitochondria and the translocation of apoptosis inducing factor ( AIF ) to the nucleus
Komura et al., Exp Cell Res 2007 (Neoplasms) : 2,5-MeC also activated endogenous p53 and induced apoptosis in U2OS cells
Takahashi et al., Int J Cancer 1993 (Breast Neoplasms) : Whereas the increases in DNA synthesis and p53 phosphorylation were inhibited by antibody to the IGF-I receptor and by 2,5-Mec, the nuclear exclusion of p53 was prevented by the antibody and also, although not significantly, by 2,5-Mec