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IFNB1 — JUN
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Ludwig et al., J Biol Chem 2001
(Influenza, Human) :
Blockade of JNK signaling at several levels of the cascade by transient expression of dominant negative kinase mutants and inhibitory proteins resulted in inhibition of virus induced JNK activation, reduced
AP-1 activity, and impaired
transactivation of the
IFN-beta promoter
Ludwig et al., J Biol Chem 2001
(MAP Kinase Signaling System) :
Blockade of JNK signaling at several levels of the cascade by transient expression of dominant negative kinase mutants and inhibitory proteins resulted in inhibition of virus induced JNK activation, reduced
AP-1 activity, and impaired
transactivation of the
IFN-beta promoter
Kim et al., J Neurochem 2002
:
IFNbeta induced
AP-1 nuclear binding activity in microglia and this was suppressed by PD98059
Takada et al., Exp Cell Res 2005
(Lymphoma, B-Cell) :
IFN-beta induced a sustained activation of
c-Jun NH2-terminal kinase 1 (JNK1) , but not extracellular signal regulated kinases ( ERKs )
Daffis et al., PLoS Pathog 2009
(West Nile Fever) :
However, pharmacological inhibition of NF-kappaB and
ATF-2/c-Jun , the two other known components of the IFN-beta enhanceosome, strongly
reduced IFN-beta gene transcription in the DKO dendritic cells