Gene interactions and pathways from curated databases and text-mining

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ANGPT2 — PDGFB

Text-mined interactions from Literome

Deguchi et al., Circ Res 1999 : Transient transfection analysis using a PDGF-B promoter-luciferase gene reporter construct reveals that Ang II induces transcriptional activation of PDGF-B chain gene, which is abolished by the expression of a dominant negative form of either ERK or JNK, but not of p38
Li et al., Zhonghua Bing Li Xue Za Zhi 2001 : Ang II is effective to activate NF-kappa B through a pathway dependent on NIK, IKK alpha and IKK beta, and induces PDGF-B transcription in the endothelial cell line ECV304
Li et al., Chin Med J (Engl) 2002 : Ang II is effective in stimulating NF-kappaB activation through a pathway dependent on NIK, IKK(alpha) and IKK(beta), and induces PDGF-B transcription in the endothelial cell line, ECV304.v
Xaymardan et al., J Exp Med 2004 (Coronary Disease...) : In vitro PDGF-AB induced vascular endothelial growth factor ( VEGF ) and angiopoietin (Ang)-2 expression in 4-mo-old rat cardiac endothelial cells, but not in 24-mo-old heart cells