◀ Back to CXCL12

CXCL12 — EVPL

Text-mined interactions from Literome

Geay et al., Cancer Res 2005 (Blast Crisis...) : p210BCR-ABL inhibits SDF-1 chemotactic response via alteration of CXCR4 signaling and down-regulation of CXCR4 expression
Chang et al., Oncogene 2009 (Leukemia, Myelogenous, Chronic, BCR-ABL Positive) : As Cdc42 is particularly important in cytoskeletal remodeling and directional sensing, these results suggest that sustained activation of Cdc42 GTPase through p210 ( Bcr-Abl ) tyrosine kinase signaling in CML cells contributes to defects in SDF-1alpha-chemotactic response due to desensitization of the actin polarization signal required for directional migration