Mahapatra et al., J Biol Chem 2003
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Trans-activation ( approximately 21-fold ) of GAL4-CREB fusion protein by secretin indicates involvement of CREB in secretin signaling to gene transcription
Mahata et al., Cell Tissue Res 2011
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In agreement, secretin increased PKA activity and induced phosphorylation of CREB and binding to Th CRE, suggesting secretin signaling to transcription via a PKA-CREB pathway