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AGT — ANGPT2
Text-mined interactions from Literome
Takamatsu et al., Pediatr Nephrol 2008
(Glomerulonephritis, IGA) :
These data suggest that activated glomerular
AGT expression is likely
involved in elevated local
ang II production and, thereby, may contribute to increased TGF-beta production and development of glomerular injury in IgAN
Nadu et al., Journal of the American Society of Hypertension : JASH 2008
:
Moreover, TGR ( A1-7 ) 3292 presented lower
Ang II levels and
angiotensinogen expression and a higher angiotensin converting enzyme 2 (ACE2) expression in LV. Isoproterenol treatment
increased cardiac Ang II concentration only in normal rats, which was associated with an increase in ACE2 and a decrease in Mas expression
Coezy et al., Am J Physiol 1989
(Hematoma) :
The aim of this study was to examine in Hep G2, a human hepatoma derived cell line, the presence of angiotensin II (ANG II) receptors and the
effect of
ANG II and its analogues on
angiotensinogen production ... Results of these studies show that the Hep G2 cell possesses specific ANG II receptors and that [ Sar1 ]
ANG II induces a dose dependent inhibition of
angiotensinogen production in this system
Klett et al., Clin Exp Hypertens A 1987
:
In the isolated perfused liver,
ANG II induced a similar
increase of
angiotensinogen secretion, without affecting albumin and total protein secretion rates
Köller et al., Neurosci Lett 1979
:
The presence of
angiotensinogen , the precursor of angiotensin II (ANG II), in brain tissue and in cerebrospinal fluid (CSF)
allows stimulation of endogenous brain
ANG II by renin