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PPARA — VEGFA

Text-mined interactions from Literome

Fauconnet et al., J Biol Chem 2002 (Urinary Bladder Neoplasms) : This effect is potentiated by an RXR ( retinoid-X-receptor ), selective retinoid LG10068 providing support for a PPAR agonist-specific action on VEGF expression
Meissner et al., Circ Res 2004 : PPARalpha activators inhibit vascular endothelial growth factor receptor-2 expression by repressing Sp1 dependent DNA binding and transactivation
Pola et al., J Mol Cell Cardiol 2004 (Corneal Neovascularization) : In this study, the in vivo angiogenic properties of different PGI2 analogs and the potential relationship between PPAR mediated pathways, vascular endothelial growth factor ( VEGF ), and angiogenesis were investigated
Sato et al., Nihon rinsho. Japanese journal of clinical medicine 2005 (Neovascularization, Pathologic) : PPARalpha and gamma ligands not only inhibit VEGF-receptor 2 expression but also act as blocker of VEGF-receptor signaling
Hwang et al., J Biol Chem 2012 (Colonic Neoplasms) : Based on these data, we propose a model for PPAR-d activated VEGFA transcription that relies on ß-catenin mediated chromatin looping as a prerequisite for the activation