Gene interactions and pathways from curated databases and text-mining

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MIF — VEGFA

Text-mined interactions from Literome

Ren et al., Int J Cancer 2003 (Carcinoma, Hepatocellular...) : MIF induced a significant dose dependent increase in IL-8 and VEGF production
Ren et al., Oncogene 2004 (Neuroblastoma) : In addition, we found that MIF induced a significant dose dependent increase of vascular endothelial growth factor and interleukin-8 secretion
Ren et al., Ann Surg 2005 (Carcinoma, Squamous Cell...) : In addition, in vitro MIF stimulation of esophageal cancer cell lines induced a dose dependent increase in VEGF and IL-8 secretion
Bondza et al., J Reprod Immunol 2008 (Adenocarcinoma...) : Moreover, immunocytofluorescence revealed positive VEGF immunostaining compared to control, and analysis by ELISA of VEGF release in culture supernatants demonstrated that MIF ( 25 ng/ml ) significantly induced VEGF secretion at 12 and 24 h
Xu et al., Cancer Lett 2008 (Breast Neoplasms...) : In addition, we investigated the expression of MIF in MDA-MB-231, MCF-7 ( breast cancer cell lines ) and MCF-10A ( epithelial cell line ) cells, and its effect on VEGF and IL-8 ... Exogenous MIF did not cause endothelial tube formation and migration but induced a dose dependent increase in VEGF and IL-8 secretion in breast cancer cell lines
Han et al., Clin Orthop Relat Res 2008 (Bone Neoplasms...) : MIF expression correlated with microvessel density and induced a dose dependent increase in vascular endothelial growth factor
Coleman et al., J Immunol 2008 (Carcinoma, Non-Small-Cell Lung...) : Because MIF has important autocrine effects on normal and transformed cells, we investigated whether autocrine MIF and its only known family member, D-dopachrome tautomerase (D-DT), promote the expression of proangiogenic factors CXCL8 and vascular endothelial growth factor in NSCLC cells