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IL18 — VEGFA

Text-mined interactions from Literome

Gloddek et al., J Endocrinol 1999 : Pituitary adenylate cyclase activating polypeptide, interleukin-6 and glucocorticoids regulate the release of vascular endothelial growth factor in pituitary folliculostellate cells
Tsuji et al., Biol Pharm Bull 2000 : Effects of sulfhydryl compounds on interleukin-1 induced vascular endothelial growth factor production in human synovial stromal cells
Matsumoto et al., Nephron 2000 (Nephrosis, Lipoid) : Taken together, our results indicate that both IL-18 and IL-12 contribute to the VPF production in vitro and suggest that they play key roles in the complexity of cytokine regulation in the pathophysiology of VPF
Coskun et al., Clin Exp Immunol 2004 (Breast Neoplasms...) : Both serum VEGF and IL-18 levels decreased after tamoxifen therapy ( P = 0.051, P < 0.05, respectively ). Serum VEGF levels increased in patients with endometrial thickness, while patients without endometrial thickness had a significant reduction in serum VEGF levels after therapy ( P < 0.05 ). Serum nitrate + nitrite levels increased after the therapy, but this was not statistically significant ( P > 0.05 )
Inoue et al., Rheumatol Int 2005 (Osteoarthritis, Hip...) : Induction of vascular endothelial growth factor and matrix metalloproteinase-3 ( stromelysin ) by interleukin-1 in human articular chondrocytes and synoviocytes
Cho et al., Immunol Lett 2006 (Arthritis, Rheumatoid) : Interleukin-18 induces the production of vascular endothelial growth factor ( VEGF ) in rheumatoid arthritis synovial fibroblasts via AP-1 dependent pathways ... In present study, we examined the effect of IL-18 on VEGF production in fibroblast-like synoviocytes ( FLS ) isolated from the patients with RA ... IL-18 dose-dependently increased the production of VEGF ... The effect of IL-18 on VEGF production appeared to be as potent as IL-1beta, whereas tumor necrosis factor (TNF)-alpha and interferon (IFN)-gamma showed little effects on VEGF production ... AP-1-specific inhibitor Curcumin dose-dependently abrogated the effect of IL-18 on VEGF production
Amin et al., Arthritis Rheum 2007 (Arthritis, Rheumatoid) : IL-18 significantly enhanced the production of SDF-1alpha/CXCL12, MCP-1/CCL2, and VEGF in RA ST fibroblasts, in a time- and concentration dependent manner ... In contrast, IL-18 did not induce secretion of RA ST fibroblast MCP-1/CCL2 or VEGF via p38 MAPK ... IL-18 induced RA ST fibroblast production of VEGF was mediated mainly by JNK-2, PKCalpha, and NFkappaB
Schmeding et al., Transplantation 2010 (Fatty Liver) : Analysis of liver enzymes, histology ( hematoxylin-eosin and periodic acid Schiff stain ), immunostaining ( terminal deoxynucleotide transferase- mediated dUTP nick-end labeling, hypoxyprobe, and tumor necrosis factor-alpha ), and reverse transcriptase-polymerase chain reaction of cytokine messenger RNA ( interleukin-1 , interleukin-6, hypoxia induced factor-1 alpha, vascular endothelial growth factor , and hepatocyte growth factor ) were performed at defined time points ( 2, 4.5, 24, 48 hr, and 7 days postoperatively )
Chew et al., BMC cancer 2010 (Nasopharyngeal Neoplasms...) : The present study examined the roles of EBV latent membrane protein-1 (LMP1), interleukin-6 (IL-6), interleukin-10 (IL-10), transforming growth factor-beta 1 ( TGF-ß1 ) and laminin in the regulation of matrix-metalloproteinases ( MMPs ) and vascular endothelial growth factor ( VEGF ) in NPC
Choe et al., Joint Bone Spine 2012 (Arthritis, Rheumatoid...) : Tacrolimus ( FK506 ) inhibits interleukin-1ß induced angiopoietin-1, Tie-2 receptor, and vascular endothelial growth factor through down-regulation of JNK and p38 pathway in human rheumatoid fibroblast-like synoviocytes
Ben-Av et al., FEBS Lett 1995 (Arthritis, Rheumatoid...) : Induction of vascular endothelial growth factor expression in synovial fibroblasts by prostaglandin E and interleukin-1 : a potential mechanism for inflammatory angiogenesis
Kvanta et al., Curr Eye Res 1995 : Both interleukin-1 and transforming growth factor beta induced VEGF expression in choroidal fibroblasts although with different time courses ... By using Western blotting, it was further found that stimulation with interleukin-1 induced VEGF protein expression in choroidal fibroblasts but not in RPE cells