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HDAC1 — VEGFA

Text-mined interactions from Literome

Sawa et al., Brain Tumor Pathol 2002 (Brain Neoplasms...) : We investigated the effects of histone deacetylase (HDAC) inhibitors such as sodium butyrate ( SB ) and trichostatin A (TSA) on the expression of vascular endothelial growth factor ( VEGF ) by human glioblastoma T98G, U251MG, and U87MG cells ... These results suggest that HDAC inhibitors reduce VEGF secretion and modulate the expression of the other VEGF family members, and therefore may inhibit angiogenesis in glioblastoma tissues
Nakajima et al., Pancreas 2007 (Acute Disease...) : Apoptosis of ileal mucosa was accelerated in SAP , and VEGF significantly reduced the apoptosis ... Microvessel counts were significantly reduced in SAP , and VEGF significantly increased them
Reynoso-Roldán et al., Clin Invest Med 2012 (Anoxia...) : In hypoxic tumoral tissues, vascular endothelial growth factor ( VEGF ) expression is positively regulated by histone deacetylase 1 (HDAC1) and negatively regulated by the tumour suppressor protein von Hippel-Lindau (VHL) via transforming growth factor-alpha ( HIF-1alpha ) ... Although HIF-1alpha is constitutively expressed in normal keratinocytes, it is not known if HDAC1 and VHL can regulate VEGF production in these cells
Kashyap et al., Mol Oncol 2013 : We show that functional depletion of LSD1 expression using siRNA in prostate cancer cells decreases VEGF-A and blocks androgen induced VEGF-A , PSA and Tmprss2 expression