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EPHB2 — PDLIM7

Text-mined interactions from Literome

Chuang et al., Blood 2005 (Lymphohistiocytosis, Hemophagocytic) : LMP1 mediated SAP/ERK/IFN-gamma signals appear to act via the TNF receptor associated factor (TRAF)2,5/nuclear factor kappaB (NF-kappaB) pathway, since dominant negative TRAF2/5 and NF-kappaB inhibitor could rescue SAP expression and downregulate IFN-gamma
Kung et al., J Virol 2011 : Epstein-Barr virus LMP1 activates EGFR, STAT3, and ERK through effects on PKCdelta ... Interestingly, inhibition of PKCd also inhibited constitutive phosphorylation of EGFR and LMP1-CTAR1 induced phosphorylation of ERK ... These findings indicate that LMP1 activates multiple distinct signaling pathways and suggest that PKCd functions as a master regulator of EGFR, STAT3, and ERK activation by LMP1-CTAR1
Liu et al., PloS one 2012 (Nasopharyngeal Neoplasms) : ERK-specific small interfering RNA blunts LMP1 induced kappa light chain gene expression ... PD98059 treatment also leads to a concentration dependent inhibition of LMP1 induced Ets-1 expression and phosphorylation, which corresponds with a dose dependent attenuation of LMP1 induced ERK phosphorylation and kappa light chain expression