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CTNND1 — EPHB2
Text-mined interactions from Literome
Blaukat et al., J Biol Chem 1999
:
Grb2 with a deleted carboxyl-terminal Src homology 3 domain partially blocked Pyk2 induced ERK and JNK pathways, whereas expression of dominant interfering mutants of
p130Cas or Crk specifically
inhibited JNK but not
ERK activation by Pyk2
Kyaw et al., Mol Pharmacol 2004
:
Ang II-stimulated tyrosine phosphorylation of Src and
Cas and
activation of
ERK1/2 and JNK, but not p38, were potently inhibited by Src family tyrosine kinase inhibitors, herbimycin A ( HA ) and PP2 ... Ang II-stimulated Src and
Cas association, tyrosine phosphorylation of Cas, and
activation of
ERK1/2 and JNK were suppressed in kinase-inactive Src ( KI Src ) -overexpressed RASMC
O'Donnell et al., Microvasc Res 2011
(Inflammation) :
Results indicated that loss of
p120ctn increased phosphorylated
ERK1/2 , and a MEK1 inhibitor ( PD98059 ) prevented NF?B nuclear translocation
Dan et al., OncoTargets and therapy 2012
:
EGF
activated FAK ( Y397 ) and
p130cas ( Y410 ) phosphorylation, while Fn activated
ERK general phosphorylation
Kim et al., BMB Rep 2012
(Melanoma, Experimental) :
The
CaS reduced intracellular cAMP levels to unstimulated levels and
activated ERK phosphorylation within 30 min