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HSPG2 — MCOLN1
Text-mined interactions from Literome
Johansson et al., Br J Pharmacol 2007
:
The partial inhibitor of both ROCs and SOCs,
Mg2+ , and the SOC inhibitors, dextromethorphan, SKF-96365 ( 1- [ beta- ( 3- ( 4-methoxyphenyl ) propoxy ) -4-methoxyphenethyl ] -1H-imidazole HCL ) and 2-APB ( 2-aminoethoxydiphenyl borate ),
inhibited PLC activity at low concentrations of orexin-A, but were not as effective as TEA
Chien et al., J Biol Chem 1990
:
Fourth, the activities exhibit absolute specificity in terms of activation by Mg2+ and Ca2+, i.e. the PtdIns
PLC is
activated only by
Mg2+ and the PtdInsP2 PLC is activated only by Ca2+
Gerasimene et al., Prikl Biokhim Mikrobiol 1985
:
Metal ions had no effect on the activity of PI-PLC, whereas
Mg2+ and Co2+ in concentrations from 1 to 5 mM highly
activated SM-PLC