Gene interactions and pathways from curated databases and text-mining

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IGF1 — TF

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Meroni et al., J Endocrinol 2004 (MAP Kinase Signaling System) : In addition, the analysis of the participation of a MAPK pathway in IGF-I regulation of Sertoli cell biological responses showed that the MAPK kinase inhibitors, PD98059 and U0126, decreased IGF-I stimulated transferrin secretion while not modifying IGF-I stimulated lactate levels
Herman et al., Int J Oncol 2007 (Neoplasm Invasiveness...) : Transferrin increased binding of insulin growth factor (IGF)-1 to the activated IGF-1 receptor, and IGF-1 mimicked the invasive and adhesive effects of transferrin
Zvibel et al., J Cell Physiol 1995 (Carcinoma, Hepatocellular...) : In H4A7C2 cells, IGF II reduced CK19 and OC.3 protein levels and GGT, transferrin , and HNF-3 beta mRNAs