Gene interactions and pathways from curated databases and text-mining

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IFNG — SLPI

Text-mined interactions from Literome

Jin et al., Methods 1998 (Inflammation) : Interferon-gamma (IFN-gamma) , which corrects the defective LPS response in Lps ( d ) macrophages, suppressed the LPS induced expression of SLPI and restored LPS response to SLPI overexpressing macrophages
Shioi et al., Circ Res 2002 : TNF-alpha and OSM, only when applied together, increased ALP activities and in vitro calcification in HVSMCs in the presence of IFN-gamma and 1,25 ( OH ) 2D3
Yoshihara et al., Lymphokine Res 1990 (Osteosarcoma) : The TNF alpha induced inhibition of proliferation and ALP activity was further potentiated by interferon (IFN) gamma
Hirose et al., Meikai Daigaku Shigaku Zasshi 1989 (Bone Resorption) : We examined here the effects of recombinant mouse interferon-gamma ( rmIFN-G ) on DNA and collagen synthesis, and on alkaline phosphatase (ALP) activity, in the osteoblastic cell line ( MC3T3-E1 ) under confluent culture conditions
Katayama et al., Meikai Daigaku Shigaku Zasshi 1989 (Osteosarcoma) : Since recombinant interferon gamma inhibits stimulation of bone resorption by these cytokines, we examined here the effects of recombinant human interferon gamma ( rhIFN-G ) on DNA synthesis and alkaline phosphatase (ALP) activity of a human osteoblastic osteosarcoma cell line, SaOS2, under preconfluent culture conditions
Jin et al., Cell 1997 : IFN gamma suppressed expression of SLPI and restored LPS responsiveness to SLPI producing cells