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CD14 — IFNG

Text-mined interactions from Literome

Brown et al., J Immunol 2001 : Treatment of cells with NaClO ( 3 ), an inhibitor of sulfation, prevented HA binding in a significant percentage of CD14 ( + ) PBMC induced by TNF-alpha, LPS, IL-1beta, or IFN-gamma
Tamai et al., Infect Immun 2002 : To elucidate the mechanism of the priming effects of IFN-gamma for the LPS response by HGF, we examined whether IFN-gamma regulated expression of CD14 , Toll-like receptor 2 (TLR2), TLR4, MD-2, and MyD88, all of which are molecules suggested to be associated with LPS signaling ... In CD14 ( high ) HGF, IFN-gamma markedly up-regulated CD14 and MyD88 but not TLR4 protein and MD-2 mRNA expression, while in CD14 ( low ) HGF, IFN-gamma slightly increased MyD88 and scarcely affected CD14, TLR4 protein, and MD-2 mRNA levels
Merlin et al., Eur J Immunol 2002 : Priming with P. acnes led to a moderate, mainly IFN-gamma dependent up-regulation of CD14
Payne et al., J Interferon Res 1992 : The effects of interferon-gamma and bacterial lipopolysaccharide on CD14 expression in human monocytes ... The effects of interferon-gamma (IFN-gamma) on CD14 expression have not been clearly established ... The purpose of this investigation was to examine the effects of IFN-gamma alone and IFN-gamma followed by bacterial LPS on CD14 expression
Harigai et al., Arthritis Rheum 2004 (Arthritis, Rheumatoid...) : Specific inhibitors of MAPK/ERK-1/2 kinases and p38 MAPK significantly reduced the production of TNFalpha and IL-1beta by rsCD154 plus IFNgamma stimulated CD14+ synovial cells, and also inhibited production of these cytokines by freshly isolated synovial cells from RA patients
Upham et al., J Allergy Clin Immunol 2004 (Hypersensitivity) : The magnitude of HLA-DR upregulation on IFN-gamma stimulated cord blood CD14 + monocytes was consistently correlated with allergen induced, but not mitogen induced, lymphoproliferation at birth
Lappegård et al., Proc Natl Acad Sci U S A 2009 (Inflammation) : IL-1 receptor antagonist (IL-1ra) and IFN-gamma inducible protein 10 ( IP-10 ) were fully dependent on CD14 and inversely regulated by complement, that is, complement deficiency and complement inhibition enhanced their release
Kim et al., Mol Med 2013 : HMGB1 induces the release of monocyte chemotactic protein 1 (MCP-1), interferon gamma induced protein 10 ( IP-10 ) and macrophage inflammatory protein 1a ( MIP-1a ) in a TLR4- and CD14 dependent manner
Backman et al., Cancer Res 1994 (Breast Neoplasms) : In our model, IFN-gamma did not up-regulate or down-regulate HER-2/neu protein expression on our targets or affect the level of CD14 antigen expression on our MDM. Although IFN-gamma is a potent activator of monocytes/macrophages and can enhance certain tumoricidal mechanisms, our data show that antibody dependent phagocytosis through the type II Fc receptor is inhibited by IFN-gamma priming
Car et al., J Exp Med 1994 (Body Weight...) : Thus, depressed TNF synthesis, diminished expression of CD14 , and low plasma LPS binding capacity, in addition to blocked IFN-gamma signaling in the mutant mice, likely to combine to manifest in the resistant phenotype of IFN gamma R-/- mice to endotoxin
Becher et al., J Neurosci Res 1996 : Surface CD14 expression can be down-regulated by interaction with its ligand lipopolysaccharide (LPS), and by the T-helper ( Th1 ) cytokine interferon-gamma (IFN-gamma) or the Th2 cytokine interleukin-4 (IL-4) ... IFN-gamma augments CD14 transcription, suggesting cleavage of surface CD14 consequent to general cell activation