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AKT3 — CIB1

Text-mined interactions from Literome

Festuccia et al., Endocr Relat Cancer 2009 (Disease Models, Animal...) : In vivo, azacitidine ( 0.8 mg/kg i.p. ) reduced tumor proliferation and induced apoptosis in both xenografts upmodulating the expression of p16INKA, Bax, Bak, p21/WAF1, and p27/KIP1 , and inhibiting the activation of Akt activity and the expression of cyclin D1, Bcl-2, and Bcl-XL
Lee et al., Mol Cells 2009 : Lf ( Fe ( 3+ ) ) immediately induced Akt phosphorylation at Ser473, which subsequently induced the phosphorylation of two G1-checkpoint Cdk inhibitors, p21 ( Cip/WAF1 ) and p27 ( kip1 )
Vaid et al., Carcinogenesis 2010 (Cell Transformation, Neoplastic...) : Western blot analysis revealed that honokiol : ( i ) inhibited the levels of cyclins D1, D2 and E and associated cyclin dependent kinases (CDKs)2, CDK4 and CDK6, ( ii ) upregulated Cip/p21 and Kip/p27 and ( iii ) inhibited the levels of phosphatidylinositol 3-kinase and the phosphorylation of Akt at Ser ( 473 ) in UVB induced skin tumors